ChemBioCalc

Dozens of smart lab tools for chemistry, biology & pharma — now with step-by-step Design of Experiments (DoE/RSM) wizard. Calculate, optimize, learn with citations.

ChemBioCalc Pro - Professional calculation suite for Chemistry, Biology, Pharmaceutical, and Molecular Biology laboratories. Compliant with ICH Q2(R2), EMA M10, USP 621, and ICH Q1E. PROFESSIONAL TOOLS CHEMISTRY

• Solution preparation and dilution (C1V1 = C2V2)
• Stoichiometry, empirical formula, reaction yield
• Acid-base, buffers (Henderson-Hasselbalch), pH, Ksp
• Thermochemistry, gas laws, electrolysis (Faraday)
• Adsorption isotherms (Langmuir, Freundlich, Temkin, Dubinin-Radushkevich)
• Adsorption kinetics and thermodynamics (van t Hoff)
• UV-Vis spectrophotometer and Beer-Lambert
• IR/NMR/MS spectrum quick interpretation
• RGB Colorimetry (image-based concentration analysis)
• Standard curve, LOD/LOQ calculation
• Molecule visualization (SMILES, PNG/PDF export)
• HPLC Column Selector (27 real columns: Waters, Phenomenex, Agilent)
• HPLC Method Transfer (USP 621 geometric scaling)
• HPLC Sequence Builder (optimal injection order for validation)
• Multi-Component UV-Vis (matrix solving)
• Method Validation (ICH Q2(R2) + EMA M10) PHARMACY
• Release kinetics 8 models (Zero/First-order, Higuchi, Korsmeyer-Peppas, Hixson-Crowell, Baker-Lonsdale, Weibull, Hopfenberg)
• Dissolution similarity (f1/f2)
• Stability analysis Arrhenius + Shelf Life in one workflow (ICH Q1E)
• Particle size (d10, d50, d90, Span)
• Encapsulation efficiency (EE%, DL%)
• Pharmacokinetics (1-comp and 2-Compartment PopPK + variability)
• Dose converter (NOAEL to HED to MRSD, FDA Phase 1)
• Renal/Hepatic dose adjustment (Cockcroft-Gault, MDRD-4, CKD-EPI 2021, Child-Pugh)
• Bioequivalence (90% CI, GMR, 80-125% rule)
• IV drip calculation, pediatric dose MOLECULAR BIOLOGY
• DNA/RNA calculations (concentration, Tm, copy number, purity)
• PCR Primer Tm (Wallace/GC/Nearest-Neighbor), gradient, master mix
• qPCR Analysis ddCt (Livak), standard curve, primer efficiency
• Primer Designer (automatic design from template)
• Protein Suite (concentration, extinction e280, dilution)
• Protein MW and pI calculation (from amino acid sequence)
• Restriction Map and Cloning (Gibson Assembly)
• CRISPR Guide RNA design
• Plasmid Map
• NGS Coverage (Lander-Waterman, WGS/WES/ctDNA/RNA-seq)
• Electrophoresis, Western Blot, ELISA (4-PL curve)
• Enzyme kinetics (Michaelis-Menten, Vmax, Km, kcat)
• Cell culture, CFU and serial dilution LAB NOTEBOOK Record experiments with photos, tags, projects. Export to PDF or Excel. ABBREVIATION GLOSSARY (NEW) Tappable explanations for 105+ scientific abbreviations. Tap any blue abbreviation in any module to learn its meaning: LOD, LOQ, Cmax, AUC, ddCt, pI, kcat and more. BILINGUAL Turkish and English all modules, reports, and glossary. REPORTING PDF (with automatic citation block useful for publications), Excel, JSON export. One-tap image sharing. PRIVACY Data stays on your device. No cloud account, no anonymous tracking, no ad trackers. PRO SUBSCRIPTION Unlimited calculations, all Pro tools (HPLC suite, Method Validation, PopPK, NGS Coverage, etc.), Lab Notebook Pro, ad-free experience. Weekly/monthly/yearly plans. Terms of Use (EULA): https://www.apple.com/legal/internet-services/itunes/dev/stdeula/ Privacy Policy: https://chembiocalc.com/privacy Contact: support@chembiocalc.com Feedback: feedback@chembiocalc.com Web: https://www.chembiocalc.com