ChemBioCalc: Lab Assistant

ChemBioCalc Pro - Professional calculation suite for Chemistry, Biology, Pharmaceutical, and Molecular Biology laboratories. Calculations are referenced to ICH Q2(R2), EMA M10, USP 621 and ICH Q1E. PROFESSIONAL TOOLS CHEMISTRY

• Solution preparation and dilution (C1V1 = C2V2)
• Stoichiometry, empirical formula, reaction yield
• Acid-base, buffers (Henderson-Hasselbalch), pH, Ksp
• Thermochemistry, gas laws, electrolysis (Faraday)
• Adsorption isotherms (Langmuir, Freundlich, Temkin, Dubinin-Radushkevich)
• Adsorption kinetics and thermodynamics (van t Hoff)
• UV-Vis spectrophotometer and Beer-Lambert
• IR/NMR/MS spectrum quick interpretation
• RGB Colorimetry (image-based concentration analysis)
• Standard curve, LOD/LOQ calculation
• Molecule visualization (SMILES, PNG/PDF export)
• HPLC Column Selector (27 real columns: Waters, Phenomenex, Agilent)
• HPLC Method Transfer (USP 621 geometric scaling)
• HPLC Sequence Builder (optimal injection order for validation)
• Multi-Component UV-Vis (matrix solving)
• Method Validation (ICH Q2(R2) + EMA M10) PHARMACY
• Release kinetics 8 models (Zero/First-order, Higuchi, Korsmeyer-Peppas, Hixson-Crowell, Baker-Lonsdale, Weibull, Hopfenberg)
• Dissolution similarity (f1/f2)
• Stability analysis Arrhenius + Shelf Life in one workflow (ICH Q1E)
• Particle size (d10, d50, d90, Span)
• Encapsulation efficiency (EE%, DL%)
• Pharmacokinetics (1-comp and 2-Compartment PopPK + variability)
• Dose converter (NOAEL to HED to MRSD, FDA Phase 1)
• Renal/Hepatic dose adjustment (Cockcroft-Gault, MDRD-4, CKD-EPI 2021, Child-Pugh)
• Bioequivalence (90% CI, GMR, 80-125% rule)
• IV drip calculation, pediatric dose MOLECULAR BIOLOGY
• DNA/RNA calculations (concentration, Tm, copy number, purity)
• PCR Primer Tm (Wallace/GC/Nearest-Neighbor), gradient, master mix
• qPCR Analysis ddCt (Livak), standard curve, primer efficiency
• Primer Designer (automatic design from template)
• Protein Suite (concentration, extinction e280, dilution)
• Protein MW and pI calculation (from amino acid sequence)
• Restriction Map and Cloning (Gibson Assembly)
• CRISPR Guide RNA design
• Plasmid Map
• NGS Coverage (Lander-Waterman, WGS/WES/ctDNA/RNA-seq)
• Electrophoresis, Western Blot, ELISA (4-PL curve)
• Enzyme kinetics (Michaelis-Menten, Vmax, Km, kcat)
• Cell culture, CFU and serial dilution LAB NOTEBOOK Record experiments with photos, tags, projects. Export to PDF or Excel. ACCOUNT AND SYNC (NEW) Optional account with email, Apple or Google sign-in. Sync your lab notebook, calculation history and validation projects across your devices. The app stays fully usable without an account. ABBREVIATION GLOSSARY Tappable explanations for 131 scientific abbreviations. Tap any blue abbreviation in any module to learn its meaning: LOD, LOQ, Cmax, AUC, ddCt, pI, kcat and more. BILINGUAL Turkish and English all modules, reports, and glossary. REPORTING PDF (with automatic citation block useful for publications), Excel, JSON export. One-tap image sharing. PRIVACY AND ADS The app works fully without an account, and your calculations run on your device. Create an account only if you want cloud sync - then your lab notebook, calculation history and validation projects are stored on our servers so your devices stay in sync. The free version is supported by ads. Ads use a device advertising identifier and usage data, and this data may be shared with advertising partners. Pro removes all ads. You can delete your account and all synced data at any time from Settings, or at https://chembiocalc.com/delete-account PRO SUBSCRIPTION Unlimited calculations, all Pro tools (HPLC suite, Method Validation, PopPK, NGS Coverage, etc.), Lab Notebook Pro, ad-free experience. Monthly and yearly plans. Terms of Use (EULA): https://www.apple.com/legal/internet-services/itunes/dev/stdeula/ Privacy Policy: https://chembiocalc.com/privacy Contact: support@chembiocalc.com Feedback: feedback@chembiocalc.com Web: https://www.chembiocalc.com