ChemBioCalc

ChemBioCalc — a professional calculation tool designed for analytical laboratories. 50+ specialized modules in chemistry, molecular biology, and pharmacy, compliant with ICH/EMA/USP standards.

🎓 WHO IS IT FOR?
• Analytical chemists and QC lab technicians
• Molecular biology researchers
• Pharmacy and clinical research professionals
• Chemistry, biology, and pharmacy students
• Validation and method development specialists

🔬 FREE TOOLS
• pH/pOH (acid-base, comma/dot sensitive)
• Solution preparation (M, %w/v, ppm, molality)
• Buffer — Henderson-Hasselbalch
• Concentration converter
• Equation balancing & Stoichiometry
• Mole / molar mass (including Ca(OH)₂, K₃[Fe(CN)₆], hydrate)
• Dilution (C₁V₁ = C₂V₂)
• Thermochemistry, Gas Law, Electrolysis
• Ksp and Titration simulator
• Empirical formula & Reaction yield
• DNA/RNA concentration, Tm calculation
• PCR master mix Primary Tm
• Cell culture, CFU counting
• Protein MW & pI
• IV drip rate, Pediatric dose
• Periodic table (118 elements)
• SDS safety cards
• Molecule visualizer (SMILES)
• Lab timer

💎 PRO MODULES

🔬 Chemistry Pro:
• Method Validation Suite (ICH Q2(R2) + EMA M10)
Linearity, Accuracy, Precision, LOD/LOQ, Robustness, Stability — analyst commentary in each section
• Multi-Component UV-Vis (Beer-Lambert matrix)
• HPLC Method Transfer (USP <621> geometric scaling)
• HPLC Column Selector (HSM-based phase recommendation)
• Standard Curve & Calibration (R², LOD/LOQ)
• Arrhenius Plot (Ea, A)
• RGB Colorimetry (with camera)
• Adsorption isotherms (Langmuir, Freundlich, Temkin)
• Reaction Kinetics & Thermodynamics
• IR Spectrum, Gel/TLC Analysis

🧬 MolBio Pro:
• NGS Coverage Calculator (Lander-Waterman + Poisson)
• qPCR ΔΔCt analysis & throughput
• Cloning (Gibson, ligation)
• Primer designer
• CRISPR sgRNA (PAM screening, on/off-target)
• Restriction map (30 enzymes)
• Plasmid map
• Western blot densitometry
• Enzyme kinetics (Michaelis-Menten)
• ELISA 4PL standard curve

💊 Pharmacy Pro:
• 2-Compartment PopPK (IV bolus/infusion + variability simulation)
• Bioequivalence (BE) 90% CI, 80-125% rule
• Drug release • Kinetics (Higuchi, Korsmeyer-Peppas, Hopfenberg)
• Stability (Arrhenius, shelf life, ICH zone)
• Solubility test (F1/F2 similarity)
• Pharmacokinetic parameters (AUC, Cmax, t½)
• Dose conversion (BSA, allometric, NOAEL→HED)
• Renal/Hepatic dose adjustment (CrCl, Child-Pugh)
• Particle size (d10, d50, d90, Span, PDI)
• Encapsulation (EE%, DL%, Zeta)

📚 STANDARDS
ICH Q2(R2) • EMA M10 • USP <621> • ICH Q1A(R2)
Henderson-Hasselbalch • Lander-Waterman • NONMEM η

📱 FEATURES
• Bilingual (Turkish + English)
• Light/dark theme
• Lab Notebook Pro: unlimited entries, photos, tags
• PDF & Excel export
• Verified with 119 math tests
• Tablet support
• Works offline (no internet required)

🔒 PRIVACY
Your data remains on your device. No account required. GDPR compliant. Ads can be removed optionally.