Molecular Biology Courses

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Courses on the following topics are obviously present in our application.
- Part I - Structure, Function and Replication of DNA
-DNA as the heritable material
- Structure of DNA
- DNA replication: semi-conservative replication
- DNA polymerases
- Eents at the replication form
- Replication of the lagging strand
- Replication of telomeres
- Consequences of defects in telomerase
- Replication of genomes: origins of replication, cell cycle control of DNA replication
- Structure of chromosomes: DNA packaging, features of metaphase chromosomes
- Part II - Gene expression
-From DNA to RNA
- The structure and function of the gene
- Promoters and terminators
- Transcriptional initiation
- Elongation and termination
- RNA polymerases
- Structure, function and Biochemical properties of RNA
- From RNA to Protein
- The genetic code
- Codons & anticodons
- The ribosome & translation
- Gene expression in Prokaryotes: the Lac operon
- Gene expression in Eukaryotes: regulation of transcription, promoters, enhancer elements
- RNA splicing, post-transcriptional and post-translational regulation
- Part III - Molecular basis of mutation
-Causes of mutations: replication errors, mutagens
- Repair of mutations: direct repair of damaged nucleotides
- Repair by excision and DNA resynthesis
- Effects of mutations on the information content of a gene
- Examples of mutations that result in human genetic disease
- Effects of mutations on organisms: genotype and phenotype
- Effects of mutations on organisms: sex-linked mutations
- Effects of mutations on organisms: chromosome abnormalities
- PDF file
-Introduction to Genetics: A Molecular Approach
- Molecular Biology of the Cell
- Essential Cell Biology
- Molecular Biology